ea0073oc6.3 | Oral Communications 6: Calcium and Bone | ECE2021
Schoeb Manuela
, Sintenie Paula J.C.
, Haalen Femke van
, Nijhoff Michiel
, de Vries Friso
, Biermasz Nienke
, Winter Elizabeth M.
, Pereira Alberto M
, Appelman-Dijkstra Natasha
BackgroundEndogenous Cushings syndrome (CS) is detrimental to bone. The skeletal complications are characterized by decreased bone formation and increased bone resorption, resulting in decreased bone mineral density (BMD) and an increased risk of fractures at time of diagnosis. After remission of the disease, BMD improves towards normal values but fracture rate remains elevated. Therefore, components of bone quality other than BMD, such as bone mat...